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Invitrogen
SCRN2 Polyclonal Antibody
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FIGURE: 1 / 1
SCRN2 Antibody (PA5-88321) in WB
Western blot analysis of SCRN2 in extracts of various cell lines. Samples were incubated with SCRN2 Polyclonal antibody (Product # PA5-88321) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product Details
PA5-88321
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human SCRN2 (NP_6123642)
Conjugate
Form
Liquid
Concentration
1.27 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GRLWAAQRIQ EGARNISNQL SIGTDISAQH PELRTHAQAK GWWDGQGAFD FAQIFSLTQQ PVRMEAAKAR FQAGRELLRQ RQGGITAEVM MGILRDKESG ICMDSGGFRT TASMVSVLPQ DPTQPCVHFL TATPDPSRSV FKPFIFGMGV AQAPQVLSPT FGAQDPVRTL PRFQTQVDRR HTLYRGHQAA LGLMERDQDR GQQLQQKQQD LEQEGLEATQ GLLAGEWAPP LWELGSLFQA FVKRESQAYA; Positive Samples: BxPC-3, HeLa, A-375, Mouse liver, Mouse kidney, Mouse intestine
Target Information
SCRN2 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN2, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN2 may also be involved in protein secretion or the regulation of cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Secernin-2
Gene Aliases: AV001119; D11Moh48; SCRN2; SES2
UniProt ID: (Human) Q96FV2, (Mouse) Q8VCA8
Entrez Gene ID: (Human) 90507, (Mouse) 217140
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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