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Proteintech
SDCCAG8 Polyclonal Antibody
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Product Details
13471-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat,
Zebrafish
Published species
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SDCCAG8 Fusion Protein Ag4264 (1-360 aa encoded by BC032454)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
13471-1-AP can recognize all four isoforms.
Immunogen sequence: MAKSPENST LEEILGQYQR SLREHASRSI HQLTCALKEG DVTIGEDAPN LSFSTSVGNE DARTAWPELQ QSHAVNQLKD LLRQQADKES EVSPSRRRKM SPLRSLEHEE TNMPTMHDLV HTINDQSQYI HHLEAEVKFC KEELSGMKNK IQVVVLENEG LQQQLKSQRQ EETLREQTLL DASGNMHNSW ITTGEDSGVG ETSKRPFSHD NADFGKAASA GEQLELEKLK LTYEEKCEIE ESQLKFLRND LAEYQRTCED LKEQLKHKEF LLAANTCNRV GGLCLKCAQH EAVLSQTHTN VHMQTIERLV KERDDLMSAL VSVRSSLADT QQREASAYEQ VKQVLQISEE ANFEKTKHPS Q (1-360 aa encoded by BC032454)
Target Information
SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein that is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa and renal cancer tumors. Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder that is characterized by dysplasia or degeneration of the kidney, retina and cerebellum. SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on humanc chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Antigen NY-CO-8; Bardet-Biedl syndrome 16; Centrosomal colon cancer autoantigen protein; hCCCAP; mCCCAP; nephrocystin 10; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; slinky; unnamed protein product
Gene Aliases: 2700048G21Rik; 5730470G24Rik; BBS16; CCCAP; CCCAP SLSN7; hCCCAP; HSPC085; NPHP10; NY-CO-8; SDCCAG8; si:dkey-60B15.1; SLSN7
UniProt ID: (Human) Q86SQ7, (Mouse) Q80UF4, (Zebrafish) B8JK76
Entrez Gene ID: (Human) 10806, (Dog) 490374, (Rat) 305002, (Mouse) 76816, (Zebrafish) 556980
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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