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SDHAF2 Polyclonal Antibody
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Product Details
200-901-EF4
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Anti-SDHAF2 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 16 amino acid synthetic peptide near the N-terminus of human SDHAF2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SDHAF2, also named asC11orf79, SDHAF2 and SDH5, is a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. SDHAF2 has been shown to be mutated in patients with paragangliomas, also known as familial non-chromaffin paragangliomas type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SDH assembly factor 2; SDH assembly factor 2 {ECO:0000255|HAMAP-Rule:MF_03057}; Succinate dehydrogenase assembly factor 2, mitochondrial; succinate dehydrogenase assembly factor 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03057}; succinate dehydrogenase subunit 5, mitochondrial; succinate dehydrogenase subunit 5, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03057}; unnamed protein product
Gene Aliases: 0610038F07Rik; AA407634; AW049997; C11orf79; hSDH5; PGL2; PPGL2; RGD1309216; SDH5; SDHAF2
UniProt ID: (Human) Q9NX18, (Mouse) Q8C6I2, (Rat) Q5RJQ7
Entrez Gene ID: (Human) 54949, (Mouse) 66072, (Rat) 361726
tricarboxylic acid cycle
mitochondrial electron transport, succinate to ubiquinone
protein dephosphorylation
negative regulation of epithelial to mesenchymal transition
protein-FAD linkage
mitochondrial respiratory chain complex II assembly
negative regulation of canonical Wnt signaling pathway
biological_process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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