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Product Details
PA5-116425
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse, Rat, Zebrafish |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide between 147-182 amino acids from the region of (DANRE) sdhb |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
Lot-Specific |
Purification |
Protein A |
Storage buffer |
PBS |
Contains |
0.09% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2901057 |
Target Information
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ92337; Ip; iron-sulfur subunit; Iron-sulfur subunit of complex II; OTTHUMP00000044624; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex subunit B
Gene Aliases: 0710008N11Rik; fj46d06; Ip; Sdh1; Sdhb; wu:fj46d06
UniProt ID: (Mouse) Q9CQA3, (Rat) P21913, (Zebrafish) A5PL98
Entrez Gene ID: (Mouse) 67680, (Rat) 298596, (Zebrafish) 562149
Molecular Function:
dehydrogenase
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