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Invitrogen
SDHC Polyclonal Antibody
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FIGURE: 1 / 1
SDHC Antibody (PA5-49522) in WB
Western blot analysis of SDHC in various lysates. Samples were incubated with SDHC polyclonal antibody (Product # PA5-49522) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: human skeletal muscle lysate; Lane 2: mouse heart lysate; Lane 3: mouse kidney lysate. Predicted band size: 19 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-49522
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 113-144 amino acids from human SDHC.
Conjugate
Form
Liquid
Concentration
1.7 mg/mL
Amount
340 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CYBL; cytochrome B large subunit of complex II; Integral membrane protein CII-3; integral membrane protein CII-3b; large subunit of cytochrome b; Malate dehydrogenase [quinone] cytochrome b560 subunit; QPs-1; QPS1; SDHC; succinate dehydrgenase cytochrome b; succinate dehydrogenase 3, integral membrane subunit; Succinate dehydrogenase complex subunit C; succinate dehydrogenase complex subunit C integral membrane protein 15kDa; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD; Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Succinate-ubiquinone oxidoreductase cytochrome B large subunit; unnamed protein product
Gene Aliases: 0610010E03Rik; AI316496; AU019277; CYB560; CYBL; PGL3; PPGL3; QPS1; SDH3; SDHC
UniProt ID: (Human) Q99643, (Mouse) Q9CZB0
Entrez Gene ID: (Human) 6391, (Mouse) 66052
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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