Invitrogen

SDR16C5 Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

1 Published Figure

1 Reference

View all (3) SDR16C5 antibodies

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Datasheet

Protocols

Questions & Answers

Tech Support

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SDR16C5 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of SDR16C5 in human skin and heart muscle tissues using SDR16C5 Polyclonal Antibody (Product # PA5-55229). Corresponding SDR16C5 RNA-seq data are presented for the same tissues.

SDR16C5 Antibody in Western Blot (WB) — Western blot analysis of SDR16C5 in control (vector only transfected HEK293T lysate) and SDR16C5 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a SDR16C5 Polyclonal Antibody (Product # PA5-55229).

SDR16C5 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of SDR16C5 demonstrates antibody specificity. Immunohistochemical analysis of SDR16C5 using anti-SDR16C5 Polyclonal Antibody (Product # PA5-55229), shows significant staining of SDR16C5 in human skin and shows minimal or weak staining in human heart muscle tissues. The relative expression levels of SDR16C5 within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-55229

Applications	Tested Dilution	Publications
Western Blot (WB)	0.04-0.4 µg/mL	-
Immunohistochemistry (IHC)	1:50-1:200	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human
Published species	Not Applicable
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein corresponding to Human SDR16C5 View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.1 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.2, with 40% glycerol
Contains	0.02% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2647058

Product Specific Information

Immunogen sequence: CTTGCPSLLP ILEPKYAVEK IVEAILQEKM YLYMPKLLYF MMFLKSFLPL KTGLLIADYL GILHAMDGFV DQKKKL

Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 76%.

Target Information

RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TSPAN1, TMPRSS4, SDR16C5, and CTSE as Novel Panel for Pancreatic Cancer: A Bioinformatics Analysis and Experiments Validation.

Frontiers in immunology

Ye H,Li T,Wang H,Wu J,Yi C,Shi J,Wang P,Song C,Dai L,Jiang G,Huang Y,Yu Y,Li J

Published figure using SDR16C5 polyclonal antibody (Product # PA5-55229) in Immunohistochemistry

Mon Sep 27 00:00:00 EDT 2021

Bioinformatics

Protein Aliases: EPHD-2; epidermal retinal dehydrogenase 2; Epidermal retinol dehydrogenase 2; retinal short chain dehydrogenase reductase; Retinal short-chain dehydrogenase reductase 2; retSDR2; Short-chain dehydrogenase/reductase family 16C member 5

Gene Aliases: EPHD-2; RDH#2; RDH-E2; RDHE2; retSDR2; SDR16C5

UniProt ID: (Human) Q8N3Y7

Entrez Gene ID: (Human) 195814

Function(s)

retinol metabolic process retinal metabolic process keratinocyte proliferation detection of light stimulus involved in visual perception oxidation-reduction process

Process(es)

retinol dehydrogenase activity