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Product Details
PA5-55955
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
0.25-2 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human SEC14L1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.10 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2647068 |
Product Specific Information
Immunogen sequence: SVFKGAPHEI LIQIVDASSV ITWDFDVCKG DIVFNIYHSK RSPQPPKKDS LGAHSITSPG GNNVQLIDKV WQLGRDYSMV ESPLICKEGE SVQG
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
Target Information
SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SEC14-like protein 1
Gene Aliases: PRELID4A; SEC14L; SEC14L1
UniProt ID: (Human) Q92503
Entrez Gene ID: (Human) 6397
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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