FIGURE: 1 / 3
Positive Control: 293T, HepG2
Predicted Reactivity: Rat (93%), Zebrafish (83%), Xenopus laevis (83%), Bovine (96%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SEC23IP is involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: p125; SEC23-interacting protein
Gene Aliases: D7Ertd373e; MSTP053; P125; P125A; SEC23IP
UniProt ID: (Human) Q9Y6Y8