This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: NWREALAAVL TYAKPDEFSA LCDLLGTRLE NEGDSLLQTQ ACLCYICAGN VEKLVACWTK AQDGSHPLSL QDLIEKVVIL RKAVQLTQAM DTSTVGVLLA AKMSQYANLL AAQGSIAAAL AFLPDNTNQP NIMQLR
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABP125; ABP130; HSPC334; Protein transport protein Sec31A; SEC31 homolog A, COPII coating complex component; SEC31-like protein 1; SEC31-related protein A; SEC31L1; Web1-like protein; yeast Sec31p homolog
Gene Aliases: ABP125; ABP130; HSPC275; HSPC334; KIAA0905; SEC31A; SEC31L1
UniProt ID: (Human) O94979
Entrez Gene ID: (Human) 22872