This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 91%
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: ABP125; ABP130; HSPC334; Protein transport protein Sec31A; SEC31 homolog A; SEC31 homolog A (S. cerevisiae); SEC31 homolog A, COPII coating complex component; SEC31-like 1; SEC31-like protein 1; SEC31-related protein A; SEC31L1; sec31p homolog; vesicle associated protein; Vesicle-associated protein 1; Web1-like protein; yeast Sec31p homolog
Gene Aliases: 1810024J13Rik; ABP125; ABP130; AU042160; BOS_6874; cb354; HSPC275; HSPC334; KIAA0905; SEC31A; SEC31L1; sec31p; VAP1; zgc:63547