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Product Details
PA5-53119
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SEC62. Recombinant protein control fragment (Product #RP-90914).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647084
Product Specific Information
Immunogen sequence: GGRHHFWFLP NLTADVGFID SFRPLYTHEY KGPKADLKKD EKSETKKQQK SDSEEKSDSE KKEDEEGKVG PGNHGTEGSG GERHSDTDSD RREDDRSQHS SGNGNDFEMI TKEELEQQTD GDCEEDEEEE NDGETPKSS
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.
Target Information
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hTP-1; membrane protein SEC62, S.cerevisiae, homolog of; SEC62 homolog; SEC62 preprotein translocation factor; TP-1; Translocation protein 1; Translocation protein SEC62
Gene Aliases: Dtrp1; HTP1; SEC62; TLOC1; TP-1
UniProt ID: (Human) Q99442
Entrez Gene ID: (Human) 7095
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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