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Invitrogen
SEMA4A Polyclonal Antibody
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FIGURE: 1 / 1
SEMA4A Antibody (PA5-101258) in WB
Western blot analysis of SEMA4A in extracts from various samples. Samples were incubated with SEMA4A polyclonal antibody (Product # PA5-101258). Lane 1: A549 cells, blocked with antigen-specific peptides; Lane 2: A549 cells; Lane 3: Hela cells (1hUV treatment).
Product Details
PA5-101258
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SEMA4A(Accession Q9H3S1), corresponding to amino acid residues P512-P562.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SEMA4A.
Target Information
SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Sema B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; semaphorin 4A; Semaphorin-4A; Semaphorin-B; unnamed protein product
Gene Aliases: AI132332; CORD10; RP35; SEMA4A; SEMAB; SEMB; UNQ783/PRO1317
UniProt ID: (Human) Q9H3S1, (Mouse) Q62178
Entrez Gene ID: (Human) 64218, (Rat) 310630, (Mouse) 20351
angiogenesis
neural crest cell migration
adaptive immune response
T cell differentiation involved in immune response
immune system process
nervous system development
axonogenesis
axon guidance
regulation of cell shape
regulation of endothelial cell migration
negative regulation of angiogenesis
cell differentiation
positive regulation of cell migration
T-helper 1 cell differentiation
negative chemotaxis
semaphorin-plexin signaling pathway
positive regulation of excitatory synapse assembly
positive regulation of inhibitory synapse assembly
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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