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Product Details
PA5-31796
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fragment corresponding to a region within amino acids 17 and 837 of Human SEMA4B |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
0.1M tris glycine, pH 7, with 20% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2549269 |
Product Specific Information
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7, mouse brain.
Predicted reactivity: Mouse (86%), Rat (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sema C; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B; Semaphorin-4B; Semaphorin-C
Gene Aliases: KIAA1745; mKIAA1745; SEMA4B; SEMAC; SemC; UNQ749/PRO1480
UniProt ID: (Human) Q9NPR2, (Mouse) Q62179
Entrez Gene ID: (Human) 10509, (Mouse) 20352
Molecular Function:
membrane-bound signaling molecule
intercellular signal molecule
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