|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 116 and 429 of Human SEPHS2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27950 targets SEPHS2 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27950 immunogen is recombinant protein fragment corresponding to a region within amino acids 116 and 429 of Human SEPHS2.
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: selenide; Selenide, water dikinase 2; Selenium donor protein 2; Selenophosphate synthase 2; SPS2; water dikinase 2
Gene Aliases: SEPHS2; SPS2; SPS2b
UniProt ID: (Human) Q99611
Entrez Gene ID: (Human) 22928
Molecular Function: transferase
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