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SEPT6 is a member of the septin family of GTPases. Members of this family are required for cytokinesis. This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
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Protein Aliases: 2-Sep; 6-Sep; MGC16619; MGC20339; RP5-876A24.2; septin 2; Septin-6
Gene Aliases: 2810035H17Rik; C920001C06Rik; KIAA0128; mKIAA0128; SEP2; Sep6; SEPT2; SEPT6; SEPTIN6
UniProt ID: (Human) Q14141, (Mouse) Q542H3
Entrez Gene ID: (Human) 23157, (Mouse) 56526, (Rat) 691335
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