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SEPT7 Polyclonal Antibody

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Antibody Testing Data (14)

SEPT7 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 14

SEPT7 Antibody (13818-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using SEPT7 antibody 13818-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

SEPT7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

13818-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 12 publications 12 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 11 publications 11 publications

in situ PLA (PLA)

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SEPT7 Fusion Protein Ag4907 (129-437 aa encoded by BC025987)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VIDYIDSKF EDYLNAESRV NRRQMPDNRV QCCLYFIAPS GHGLKPLDIE FMKRLHEKVN IIPLIAKADT LTPEECQQFK KQIMKEIQEH KIKIYEFPET DDEEENKLVK KIKDRLPLAV VGSNTIIEVN GKRVRGRQYP WGVAEVENGE HCDFTILRNM LIRTHMQDLK DVTNNVHYEN YRSRKLAAVT YNGVDNNKNK GQLTKSPLAQ MEEERREHVA KMKKMEMEME QVFEMKVKEK VQKLKDSEAE LQRRHEQMKK NLEAQHKELE EKRRQFEDEK ANWEAQQRIL EQQNSSRTLE KNKKKGKIF (129-437 aa encoded by BC025987)

Target Information

This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Splenectomy improves erythrocyte functionality in spherocytosis based on septin abundance, but not maturation defects.

Blood advances

Cloos AS,Pollet H,Stommen A,Maja M,Lingurski M,Brichard B,Lambert C,Henriet P,Pierreux C,Pyr Dit Ruys S,Van Der Smissen P,Vikkula M,Gatto L,Martin M,Brouillard P,Vertommen D,Tyteca D

Tue Sep 12 00:00:00 EDT 2023

An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis.

Cell reports

Panagiotou TC,Chen A,Wilde A

Tue Aug 30 00:00:00 EDT 2022

An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis.

Cell reports

Panagiotou TC,Chen A,Wilde A

Tue Aug 30 00:00:00 EDT 2022

Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties.

Molecular biology of the cell

Soroor F,Kim MS,Palander O,Balachandran Y,Collins RF,Benlekbir S,Rubinstein JL,Trimble WS

Mon Feb 01 00:00:00 EST 2021

AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Wu S,Li L,Wu X,Wong CKC,Sun F,Cheng CY

Fri Oct 01 00:00:00 EDT 2021

AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Wu S,Li L,Wu X,Wong CKC,Sun F,Cheng CY

Fri Oct 01 00:00:00 EDT 2021

HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization.

Endocrinology

Wu S,Frank I,Derby N,Martinelli E,Cheng CY

Mon Nov 01 00:00:00 EDT 2021

HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization.

Endocrinology

Wu S,Frank I,Derby N,Martinelli E,Cheng CY

Mon Nov 01 00:00:00 EDT 2021

KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.

Endocrinology

Wu S,Lv L,Li L,Wang L,Mao B,Li J,Shen X,Ge R,Wong CKC,Sun F,Cheng CY

Thu Apr 01 00:00:00 EDT 2021

KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.

Endocrinology

Wu S,Lv L,Li L,Wang L,Mao B,Li J,Shen X,Ge R,Wong CKC,Sun F,Cheng CY

Thu Apr 01 00:00:00 EDT 2021

Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone.

Molecular biology of the cell

Wiegering A,Dildrop R,Vesque C,Khanna H,Schneider-Maunoury S,Gerhardt C

Thu Apr 15 00:00:00 EDT 2021

Sperm-borne miR-202 targets SEPT7 and regulates first cleavage of bovine embryos via cytoskeletal remodeling.

Development (Cambridge, England)

Wang M,Du Y,Gao S,Wang Z,Qu P,Gao Y,Wang J,Liu Z,Zhang J,Zhang Y,Qing S,Wang Y

Fri Mar 05 00:00:00 EST 2021

Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.

EMBO reports

Kandi R,Senger K,Grigoryan A,Soller K,Sakk V,Schuster T,Eiwen K,Menon MB,Gaestel M,Zheng Y,Florian MC,Geiger H

Mon Dec 06 00:00:00 EST 2021

Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.

EMBO reports

Kandi R,Senger K,Grigoryan A,Soller K,Sakk V,Schuster T,Eiwen K,Menon MB,Gaestel M,Zheng Y,Florian MC,Geiger H

Mon Dec 06 00:00:00 EST 2021

The septin cytoskeleton regulates natural killer cell lytic granule release.

The Journal of cell biology

Phatarpekar PV,Overlee BL,Leehan A,Wilton KM,Ham H,Billadeau DD

Mon Nov 02 00:00:00 EST 2020

SEPT7 regulates Ca²⁺ entry through Orai channels in human neural progenitor cells and neurons.

Cell calcium

Deb BK,Chakraborty P,Gopurappilly R,Hasan G

Tue Sep 01 00:00:00 EDT 2020

Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.

Journal of cell science

Danson CM,Pearson N,Heesom KJ,Cullen PJ

Mon Sep 10 00:00:00 EDT 2018

Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.

Journal of cell science

Danson CM,Pearson N,Heesom KJ,Cullen PJ

Mon Sep 10 00:00:00 EDT 2018

Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.

Journal of cell science

Danson CM,Pearson N,Heesom KJ,Cullen PJ

Mon Sep 10 00:00:00 EDT 2018

Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.

Journal of cell science

Danson CM,Pearson N,Heesom KJ,Cullen PJ

Mon Sep 10 00:00:00 EDT 2018

Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts.

Small GTPases

Farrugia AJ,Calvo F

Mon Jan 02 00:00:00 EST 2017

Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts.

Small GTPases

Farrugia AJ,Calvo F

Mon Jan 02 00:00:00 EST 2017

Still and rotating myosin clusters determine cytokinetic ring constriction.

Nature communications

Wollrab V,Thiagarajan R,Wald A,Kruse K,Riveline D

Fri Jul 01 00:00:00 EDT 2016

Still and rotating myosin clusters determine cytokinetic ring constriction.

Nature communications

Wollrab V,Thiagarajan R,Wald A,Kruse K,Riveline D

Fri Jul 01 00:00:00 EDT 2016

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.

Cell reports

Calvo F,Ranftl R,Hooper S,Farrugia AJ,Moeendarbary E,Bruckbauer A,Batista F,Charras G,Sahai E

Tue Dec 29 00:00:00 EST 2015

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.

Cell reports

Calvo F,Ranftl R,Hooper S,Farrugia AJ,Moeendarbary E,Bruckbauer A,Batista F,Charras G,Sahai E

Tue Dec 29 00:00:00 EST 2015

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.

Cell reports

Calvo F,Ranftl R,Hooper S,Farrugia AJ,Moeendarbary E,Bruckbauer A,Batista F,Charras G,Sahai E

Tue Dec 29 00:00:00 EST 2015

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.

Cell reports

Calvo F,Ranftl R,Hooper S,Farrugia AJ,Moeendarbary E,Bruckbauer A,Batista F,Charras G,Sahai E

Tue Dec 29 00:00:00 EST 2015

Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit.

PloS one

Gera N,Yang A,Holtzman TS,Lee SX,Wong ET,Swanson KD

Mon Feb 01 00:00:00 EST 2016

Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit.

PloS one

Gera N,Yang A,Holtzman TS,Lee SX,Wong ET,Swanson KD

Mon Feb 01 00:00:00 EST 2016

Role of endothelial cell septin 7 in the endocytosis of Candida albicans.

mBio

Phan QT,Eng DK,Mostowy S,Park H,Cossart P,Filler SG

Tue Dec 17 00:00:00 EST 2013

Role of endothelial cell septin 7 in the endocytosis of Candida albicans.

mBio

Phan QT,Eng DK,Mostowy S,Park H,Cossart P,Filler SG

Tue Dec 17 00:00:00 EST 2013

Role of endothelial cell septin 7 in the endocytosis of Candida albicans.

mBio

Phan QT,Eng DK,Mostowy S,Park H,Cossart P,Filler SG

Tue Dec 17 00:00:00 EST 2013

Role of endothelial cell septin 7 in the endocytosis of Candida albicans.

mBio

Phan QT,Eng DK,Mostowy S,Park H,Cossart P,Filler SG

Tue Dec 17 00:00:00 EST 2013

Uncovering principles that control septin-septin interactions.

The Journal of biological chemistry

Kim MS,Froese CD,Xie H,Trimble WS

Fri Aug 31 00:00:00 EDT 2012

Uncovering principles that control septin-septin interactions.

The Journal of biological chemistry

Kim MS,Froese CD,Xie H,Trimble WS

Fri Aug 31 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: 7-Sep; CDC10 (cell division cycle 10, S. cerevisiae, homolog); CDC10 (cell division cycle 10, S.cerevisiae, homolog); CDC10 protein homolog; cell division cycle 10 homolog; septin 7 variant 4; Septin-7

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Gene Aliases: CDC10; CDC3; E430034N22; NBLA02942; SEPT7; SEPT7A; SEPTIN7

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UniProt ID: (Human) Q16181, (Mouse) O55131, (Rat) Q9WVC0

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Entrez Gene ID: (Human) 989, (Mouse) 235072, (Rat) 64551

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Function(s)

structural molecule activity protein binding GTP binding identical protein binding cadherin binding involved in cell-cell adhesion nucleotide binding cytoskeletal protein

Process(es)

cytokinesis mitotic nuclear division regulation of embryonic cell shape protein heterooligomerization cilium morphogenesis cell-cell adhesion positive regulation of nonmotile primary cilium assembly cell cycle cell division

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SEPT7 Polyclonal Antibody

SEPT7 Antibody (13818-1-AP) in ICC/IF

Product Details

13818-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

in situ PLA (PLA)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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