Search
Bioss
SERCA3 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
BS-19653R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Amphibian,
Human,
Mouse,
Xenopus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SERCA3, amino acids 101-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. SERCA3 has been found to co-express with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells. Due to this pattern of expression it is referred to as the non-muscle form of SERCA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: adenosine triphosphatase, calcium; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; calcium ATPase; SERCA3f; Calcium pump 3; calcium-translocating P-type ATPase; sarco/endoplasmic reticulum Ca(2+)-ATPase 3-type Ca2+ pump; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoendoplasmic reticulum Ca2+ ATPase type 3; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3; SERCA3D; SERCA3E; SR Ca(2+)-ATPase 3; unnamed protein product
Gene Aliases: ATP2A3; SERCA3; SERCA3b
UniProt ID: (Human) Q93084, (Mouse) Q64518
Entrez Gene ID: (Human) 489, (Mouse) 53313
nucleotide binding
calcium channel regulator activity
calcium-transporting ATPase activity
protein binding
ATP binding
cysteine-type endopeptidase activator activity involved in apoptotic process
calcium ion transmembrane transporter activity
ATPase activity
calcium-dependent ATPase activity
ion channel binding
metal ion binding
hydrolase activity
primary active transporter
ion transport
calcium ion transport
cellular calcium ion homeostasis
ion transmembrane transport
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
calcium ion transmembrane transport
transport across blood-brain barrier
calcium ion transport from cytosol to endoplasmic reticulum
regulation of cardiac conduction
transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support