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Product Details
PA5-21385
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,000 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide corresponding to a region within amino acids 1 and 51 of SERP1 (Uniprot ID#Q9Y6X1) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 20% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11152681 |
Product Specific Information
Recommended positive controls: A431.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ribosome associated membrane protein 4; Ribosome-attached membrane protein 4; Stress-associated endoplasmic reticulum protein 1
Gene Aliases: D3Ucla1; RAMP4; SERP1
UniProt ID: (Human) Q9Y6X1, (Mouse) Q9Z1W5
Entrez Gene ID: (Human) 27230, (Mouse) 28146
Molecular Function:
chaperone
skeletal system development
glucose metabolic process
cellular protein modification process
protein glycosylation
response to stress
plasma membrane organization
post-embryonic development
multicellular organism aging
protein transport
endoplasmic reticulum unfolded protein response
positive regulation of insulin secretion
IRE1-mediated unfolded protein response
positive regulation of translation
positive regulation of organ growth
muscle organ morphogenesis
positive regulation of growth hormone secretion
transport
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