Sequence of this protein is as follows: FAFIHKDFDV KETFFNLSKR YFDTECVPMN FRNASQAKRL MNHYINKETR GKIPKLFDEI NPETKLILVD YILFKGKWLT PFDPVFTEVD TFHLDKYKTI KVPMMYGAGK FASTFDKNFR CHVLKLPYQG NATMLVVLME KMGDHLALED YLTTDLVETW LRNMKTRNME VFFPKFKLDQ KYEMHELLRQ MGIRRIFSPF ADLSELSATG RNLQVSRVLQ RTVIEVDERG TEAVAGILSE ITAYSMPPVI KVDRPFHFMI YEETSGMLLF LGRVVNPTLL
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: plasma protein associated with liver regeneration; Protein Z-dependent protease inhibitor; PZ-dependent protease inhibitor; PZI; RASP-1; Regeneration-associated serpin 1; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; Serpin A10; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serpin peptidase inhibitor, clade A, member 10
Gene Aliases: PZI; Rasp1; SERPINA10; UNQ707/PRO1358; ZPI
Molecular Function: protease inhibitor