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          • Primary Antibodies ›
          • SERPINA7 Antibodies

          Invitrogen

          SERPINA7 Polyclonal Antibody

          View all (13) SERPINA7 antibodies

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          Cite SERPINA7 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          SERPINA7 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          SERPINA7 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SERPINA7 Antibody (PA5-110353) in WB

          Western blot analysis of SERPINA7 in extracts of various cell lines. Samples were incubated with SERPINA7 Polyclonal antibody (Product # PA5-110353) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SERPINA7 Antibody in Western Blot (WB)
          SERPINA7 Polyclonal Antibody

          Product Details

          PA5-110353

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.43 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2855764

          Product Specific Information

          Immunogen sequence: FLNDVKTLYE TEVFSTDFSN ISAAKQEINS HVEMQTKGKV VGLIQDLKPN TIMVLVNYIH FKAQWANPFD PSKTEDSSSF LIDKTTTVQV PMMHQMEQYY HLVDMELNCT VLQMDYSKNA LALFVLPKEG QMESVEAAMS SKTLKKWNRL LQKGWVDLFV PKFSISATYD LGATLLKMGI QHAYSENADF SGLTEDNGLK LSNAAHKAVL HIGEKGTEAA AVPEVELSDQ PENTFLHPII QIDRSFMLLI LERSTRSILF LGKVVNPTEA

          Target Information

          There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: mutant serpin family A member 7; RP1-82J11.2; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antipeptidase, antitrypsin), member 7; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; serine (or cysteine) proteinase inhibitor clade A (alpha-1 antiproteinase antitrypsin) member 7; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; Serpin A7; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; T4-binding globulin; TBG Glencoe; mutant TBG causing partial TBG deficiency; thyroxin-binding globulin; thyroxine binding globulin; Thyroxine-binding globulin; thyroxine-binding globulin precursor

          View more View less

          Gene Aliases: C730040N12Rik; SERPINA7; TBG; TBGQTL

          View more View less

          UniProt ID: (Human) P05543, (Mouse) P61939

          View more View less

          Entrez Gene ID: (Human) 6906, (Rat) 81806, (Mouse) 331535

          View more View less

          Function(s)
          serine-type endopeptidase inhibitor activity thyroid hormone transmembrane transporter activity hormone binding protease inhibitor
          Process(es)
          thyroid hormone transport aging post-embryonic development negative regulation of endopeptidase activity response to nutrient levels response to vitamin A response to prostaglandin E response to drug response to peptide hormone response to steroid hormone response to corticosterone
          It has to be done as per old AB suggested Products section.

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