|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues S(260) H S K D N L K G L E E L E R K(275) of human SERPINB12.|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4285 detects SERPINB12 from human samples.
PA1-4285 has been successfully tested in WB applications
The PA1-4285 immunogen is a synthetic peptide corresponding to residues S(260) H S K D N L K G L E E L E R K(275) of human SERPINB12.
Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. A novel member of the human ov-serpin gene family, SERPINB12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestines. SERPINB12 is an inhibitor of trypsin-like serine proteinases and a new functional member of the human ov-serpin family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.