|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Reacts with residues 260-275 of the human SERPINB12 protein.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. A novel member of the human ov-serpin gene family, SERPINB12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestines. SERPINB12 is an inhibitor of trypsin-like serine proteinases and a new functional member of the human ov-serpin family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.