|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthesized peptide derived from internal of human SERPINB4.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
The antibody detects endogenous levels of total SERPINB4 protein.
SERPINB4 is also called squamous cell carcinoma antigen 2 (SCCA-2) or leupin. It directly inhibits human granzyme proteolytic activity and that overexpression of SERPINB4 in HeLa cells inhibits recombinant granzyme-induced as well as NK cell-mediated cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Leupin; Leupin SERPINB4; Peptidase inhibitor 11; PI-11; protease inhibitor (leucine-serpin); SCCA-2; SCCA2/SCCA1 fusion protein; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; Serpin B4; Serpin B4 Squamous cell carcinoma antigen 2; serpin peptidase inhibitor, clade B (ovalbumin), member 4; squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Gene Aliases: LEUPIN; PI11; SCCA-2; SCCA1; SCCA2; SERPINB4
UniProt ID: (Human) P48594
Entrez Gene ID: (Human) 6318
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