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Product Details
12741-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SERPIND1 Fusion Protein Ag3637 (149-499 aa encoded by BC035028)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DNIFIAPVG ISTAMGMISL GLKGETHEQV HSILHFKDFV NASSKYEITT IHNLFRKLTH RLFRRNFGYT LRSVNDLYIQ KQFPILLDFK TKVREYYFAE AQIADFSDPA FISKTNNHIM KLTKGLIKDA LENIDPATQM MILNCIYFKG SWVNKFPVEM THNHNFRLNE REVVKVSMMQ TKGNFLAAND QELDCDILQL EYVGGISMLI VVPHKMSGMK TLEAQLTPGV VERWQKSMTN RTREVLLPKF KLEKNYNLVE SLKLMGIRML FDKNGNMAGI SDQRIAIDLF KHQGTITVNE EGTQATTVTT VGFMPLSTQV RFTVDRPFLF LIYEHRTSCL LFMGRVANPS RS (149-499 aa encoded by BC035028)
Target Information
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HC-II; Heparin cofactor 2; Heparin cofactor II; HLS2; leuserpin 2; leuserpin-2; Protease inhibitor leuserpin-2; serine (or cysteine) peptidase inhibitor, clade D, member 1; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; serine (or cysteine) proteinase inhibitor, clade D, member 1; Serpin D1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Gene Aliases: AA985900; AI303446; D22S673; HC2; HCF2; HCII; HLS2; LS2; rls2var1; SERPIND1; THPH10
UniProt ID: (Human) P05546, (Rat) Q64268, (Mouse) P49182
Entrez Gene ID: (Human) 3053, (Rat) 79224, (Mouse) 15160
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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