Recommended positive controls: HeLa, HepG2, mouse brain.
Predicted reactivity: Mouse (87%), Rat (87%), Pig (94%), Chicken (82%), Bovine (93%).
PA5-32163 detects SERPINE2 protein in formalin-fixed paraffin-embedded equine endometrial tissue.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GDN; Glia derived nexin; Glia-derived nexin; Glia-derived nexin-like protein; glial-derived neurite promoting factor; P17; Peptidase inhibitor 7; PI-7; PN-1; Protease nexin 1; Protease nexin I; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine protease inhibitor 4; Serine protease-inhibitor 4; Serpin E2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; SERPINE 2
Gene Aliases: B230326M24Rik; GDN; GDNPF; PAI-1; PI-7; PI7; PN-1; PN1; PNI; SERPINE2; Spi4
Molecular Function: protease inhibitor