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Invitrogen
SESN2 Polyclonal Antibody
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Product Details
PA5-30845
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human SESN2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Amount
54 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Raji, K562.
Predicted reactivity: Mouse (95%), Rat (96%), Rhesus Monkey (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hi95; hypoxia-responsive p53 target; hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; Sestrin-2; unnamed protein product
Gene Aliases: HI95; SES2; SESN2; SEST2
UniProt ID: (Human) P58004
Entrez Gene ID: (Human) 83667
regulation of protein phosphorylation
regulation of gluconeogenesis
fatty acid beta-oxidation
mitochondrion organization
response to glucose
positive regulation of macroautophagy
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
cellular response to nutrient levels
mitochondrial DNA metabolic process
response to insulin
cellular response to amino acid starvation
cellular response to oxidative stress
cellular response to glucose starvation
glucose homeostasis
glucose import
positive regulation of protein kinase B signaling
triglyceride homeostasis
protein K63-linked ubiquitination
cellular response to amino acid stimulus
cellular response to leucine
reactive oxygen species metabolic process
protein K6-linked ubiquitination
cellular oxidant detoxification
regulation of cAMP/PKA signal transduction
positive regulation of protein localization to nucleus
regulation of response to reactive oxygen species
negative regulation of translation in response to endoplasmic reticulum stress
regulation of TORC1 signaling
negative regulation of TORC1 signaling
positive regulation of TORC1 signaling
positive regulation of lipophagy
cellular response to leucine starvation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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