Positive Control: A431, H1299, HeLa, HepG2, Molt-4, Raji, Neuro 2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12, PC-12, Rat2, C2C12
Predicted Reactivity: Xenopus laevis (99%), Pig (100%), Chicken (100%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: HLA-DR-associated protein II; I IGAAD; I-2PP2A; IGAAD; Inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; Liver regeneration-related protein LRRGR00002; OTTHUMP00000022286; PHAPII; Phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor; Protein SET; RP11-216B9.3; SET nuclear oncogene; SET translocation; SET translocation (myeloid leukemia-associated); TAF-1a; TAF-1b; TAF-I; Template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor
Gene Aliases: 2610030F17Rik; 2PP2A; 5730420M11Rik; AA407739; Ab1-115; I-2PP2A; I2PP2A; IGAAD; IPP2A2; PHAPII; SET; StF-IT-1; TAF-I; TAF-IBETA