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Immunogen sequence: LDWVKNAQKA FDNTEGKREG YSADSAQEAS PARQNVSSAS NPENDSSHVR ITIPIKAPSL DPTNHKRKKR QSIKAVVEKI MPEKALASGI TMSSEVVNRI LSNSEGNKKD PRVPKLSKMI
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SEB; SET-binding protein
Gene Aliases: KIAA0437; MRD29; SEB; SETBP1
UniProt ID: (Human) Q9Y6X0
Entrez Gene ID: (Human) 26040
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