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Invitrogen
SETBP1 Polyclonal Antibody
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Product Details
PA5-96609
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Avian
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SETBP1 (NP_0011235821)
Conjugate
Form
Liquid
Concentration
2.59 mg/mL
Amount
259 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MESRETLSSS RQRGGESDFL PVSSAKPPAA PGCAGEPLLS TPGPGKGIPV GGERMEPEEE DELGSGRDVD SNSNADSEKW VAGDGLEEQE FSIKEANFTE GSLKLKIQTT KRAKKPPKNL ENYICPPEIK ITIKQSGDQK VSRAGKNSKA TKEEERSHSK KKLLTASDLA ASDLKGFQPQ IKDSSKEEVW KRRGGQGIPF KKQFLSQERA MCFSCPRNPF PAKPGSLTLP FHSEPAVWAQ EV; Positive Samples: NCI-H460, HeLa; Cellular Location: Nucleus
Target Information
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: KIAA0437; SEB; SET-binding protein
Gene Aliases: KIAA0437; MRD29; SEB; SETBP1
UniProt ID: (Human) Q9Y6X0
Entrez Gene ID: (Human) 26040
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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