Immunogen sequence: KLRFLIFFDD GYASYVTQSE LYPICRPLKK TWEDIEDISC RDFIEEYVTA YPNRPMVLLK SGQLIKTEWE GTWWKSRVEE VDGSLVRILF LDDKRCEWIY RGSTRLEPMF SMKTSSASAL EKKQGQLRTR PNMGAVRSKG PVVQYTQD
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
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Protein Aliases: ERG-associated protein with a SET domain, ESET; ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; Histone H3-K9 methyltransferase 4; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; KG1T; KIAA0067; KMT1E; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SET domain, bifurcated 1; TDRD21; tudor domain containing 21
Gene Aliases: ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; SETDB1; TDRD21
UniProt ID: (Human) Q15047
Entrez Gene ID: (Human) 9869