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SEZ6L Polyclonal Antibody
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Product Details
BS-6103R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SEZ6L, amino acids 701-800.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SEZ6L (seizure related 6 homolog-like) is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acupuncture induced gene 1; Acupuncture-induced protein 1-L; Brain-specific receptor-like protein B; BSRP-B; Seizure 6-like protein; seizure related gene 6-like; SEZ6L; unnamed protein product
Gene Aliases: Acig1; AI843918; AIG1; Aig1l; AW539724; BSRP-B; KIAA0927; mKIAA0927; RGD1563628; SEZ6L; SEZ6L1; UNQ2542/PRO6094
UniProt ID: (Human) Q9BYH1, (Mouse) Q6P1D5
Entrez Gene ID: (Human) 23544, (Mouse) 56747, (Rat) 304554
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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