Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-96291
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3.
Conjugate
Unconjugated
Form
Liquid
Concentration
2.56 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2808093
Product Specific Information
Immunogen sequence: SLESLDTSLF AKNPKSKGTK RDTERNKDIA FLEAQIYEYV EILGEQRHLT HENVQRKQAR TGEEREEEEE EQISESESED EENEIIYNPK NLPLGWDGKP IPYWLYKLHG LNINYNCEIC GNYTYRGPKA FQRHFAEWRH AHGMRCLGIP NTAHFANVTQ IEDAVSLWAK LKLQKASERW QPDTEEEYED SSGNVVNKKT YEDLKRQGLL; Positive Samples: B cells, A-549, HepG2, HeLa, HL-60, Mouse lung, Mouse thymus, Rat liver; Cellular Location: Nucleus speckle
Target Information
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: pre-mRNA splicing factor SF3a (60kD); SAP 61; SF3a60; spliceosome associated protein 61; Spliceosome-associated protein 61; Splicing factor 3A subunit 3; splicing factor 3a, subunit 3, 60kD; splicing factor 3a, subunit 3, 60kDa
Gene Aliases: 4930512K19Rik; 60kDa; LRRGT00093; PRP9; PRPF9; SAP61; SF3A3; SF3a60
UniProt ID: (Human) Q12874, (Mouse) Q9D554
Entrez Gene ID: (Human) 10946, (Mouse) 75062, (Rat) 313583
Molecular Function:
RNA splicing factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support