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Proteintech
SFRP5 Polyclonal Antibody
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Product Details
19177-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SFRP5 fusion protein Ag5715
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Amount
82.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MRAAAAAGGV RTAALALLLG ALHWAPARCE EYDYYGWQAE PLHGRSYSKP PQCLDIPADL PLCHTVGYKR MRLPNLLEHE SLAEVKQQAS SWLPLLAKRC HSDTQVFLCS LFAPVCLDRP IYPCRSLCEA VRAGCAPLME AYGFPWPEML HCHKFPLDND LCIAVQFGHL PATAPPVTKI CAQCEMEHSA DGLMEQMCSS DFVVKMRIKE IKIENGDRKL IGAQKKKKLL KPGPLKRKDT KRLVLHMKNG AGCPCPQLDS LAGSFLVMGR KVDGQLLLMA VYRWDKKNKE MKFAVKFMFS YPCSLYYPFF YGAAEPH
Target Information
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Frizzled-related protein 1b; FRP-1b; SARP-3; secreted apoptosis related protein 3; Secreted apoptosis-related protein 3; Secreted frizzled-related protein 5; secreted frizzled-related sequence protein 5; sFRP-5; SFRP5; similar to frizzled-like receptor, extracellular protein
Gene Aliases: AI605071; FRP1B; SARP3; SFRP5
UniProt ID: (Human) Q5T4F7, (Mouse) Q9WU66
Entrez Gene ID: (Human) 6425, (Mouse) 54612, (Rat) 309377
regulation of transcription from RNA polymerase II promoter
apoptotic process
establishment or maintenance of cell polarity
signal transduction
visual perception
negative regulation of cell proliferation
anatomical structure morphogenesis
Wnt signaling pathway
cell differentiation
negative regulation of Wnt signaling pathway
non-canonical Wnt signaling pathway
digestive tract morphogenesis
negative regulation of protein kinase B signaling
canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway
negative regulation of non-canonical Wnt signaling pathway
multicellular organism development
negative regulation of catenin import into nucleus
post-anal tail morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of JUN kinase activity
convergent extension involved in axis elongation
regulation of establishment of planar polarity
planar cell polarity pathway involved in neural tube closure
negative regulation of planar cell polarity pathway involved in axis elongation
negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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