Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 9
Immunogen sequence: MHHQVPLPPN GQMPGFGLLP TPPFPPMAQP VIPPTPPVQQ PFQASFQAQN EPLTQKPHQQ EMEVEQPCIQ EVKRHMSDNR KSRSRSASRS PK
Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 56%.
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CTD-binding SR-like protein RA4; pre-mRNA splicing SR protein rA4; SFR15; splicing factor serine alanine 15; Splicing factor, arginine/serine-rich 15; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4
Gene Aliases: KIAA1172; SCAF4; SFRS15; SRA4
UniProt ID: (Human) O95104
Entrez Gene ID: (Human) 57466
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