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Proteintech
SFRS8 Polyclonal Antibody
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Product Details
24705-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SFRS8 Fusion Protein Ag19762 (600-951 aa encoded by BC136678)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody detects 130-150 kDa SFRS8 protein.
Immunogen sequence: LDDDSDDDE ESKEGQESSS SAANTNPAVA PPCVVVEEKK PQLTQEELEA KQAKQKLEDR LAAAAREKLA QASKESKEKQ LQAERKRKAA LFLQTLKNPL PEAEAGKIEE SPFSVEESST TPCPLLTGGR PLPTLEVKPP DRPSSKSKDP PREEEKEKKK KKHKKRSRTR SRSPKYHSSS KSRSRSHSKA KHSLPSAYRT VRRSRSRSRS PRRRAHSPER RREERSVPTA YRVSRSPGAS RKRTRSRSPH EKKKKRRSRS RTKSKARSQS VSPSKQAAPR PAAPAAHSAH SASVSPVESR GSSQERSRGV SQEKEAQISS AIVSSVQSKI TQDLMAKVRA MLAASKNLQT SAS (600-951 aa encoded by BC136678)
Target Information
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: similar to the Drosophila splicing regulator, suppressor-of-white-apricot: Swiss-Prot Accession Number P12297; splicing factor SWAP homolog; Splicing factor, arginine/serine-rich 8; splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila); splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, Drosophila homolog); splicing factor, suppressor of white-apricot family; Splicing factor, suppressor of white-apricot homolog; Suppressor of white apricot protein homolog; unnamed protein product
Gene Aliases: SFRS8; SFSWAP; SWAP
UniProt ID: (Human) Q12872
Entrez Gene ID: (Human) 6433
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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