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Invitrogen
SFTPD Polyclonal Antibody
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Product Details
PA5-149258
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse SP-D, Ala20-Phe374
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collectin7; CP4; Lung surfactant protein D; PSP-D; PSP-D Surfactant protein D; Pulmonary surfactant associated protein PSP-D; pulmonary surfactant protein D; Pulmonary surfactant-associated protein D; SFTP 4; surfactant associated protein D; Surfactant associated protein pulmonary 4; surfactant, pulmonary-associated protein D
Gene Aliases: AI573415; Sftp4; Sftpd; SP-D; SPD
UniProt ID: (Rat) P35248, (Mouse) P50404
Entrez Gene ID: (Rat) 25350, (Mouse) 20390
respiratory gaseous exchange
opsonization
response to corticosteroid
negative regulation of interleukin-2 production
negative regulation of T cell proliferation
surfactant homeostasis
innate immune response
lung alveolus development
negative regulation of phagocytosis
positive regulation of phagocytosis
regulation of liquid surface tension
response to glucocorticoid
response to hyperoxia
response to growth factor
immune system process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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