The synthetic peptide sequence is 292-321aa, RSAAENAALQQLVVAKNEAAFLSMTD SKTE
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COLEC7; Collectin-7; CP4; Lung surfactant protein D; PSP-D; PSPD; pulmonary surfactant apoprotein; pulmonary surfactant protein D; Pulmonary surfactant-associated protein D; SFTP4; SFTPD; SP-D; surfactant associated protein D; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4
Gene Aliases: AI573415; COLEC7; PSP-D; PSPD; SFTP4; SFTPD; SP-D; SPD