PA5-28240 targets SGLT1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28240 immunogen is recombinant fragment corresponding to a region within amino acids 252 and 612 of Human SGLT1.
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Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally-related substances across cellular membranes. Two families of glucose transporter have been identified: the facilitated-diffusion glucose transporter family (GLUT family), also known as 'uniporters,' and the sodium-dependent glucose transporter family (SGLT family), also known as 'cotransporters' or 'symporters' (Wright et al., 1994 [PubMed 7823022]). The SLC5A1 gene encodes a protein that is involved in the active transport of glucose and galactose into eukaryotic and some prokaryotic cells.
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Protein Aliases: D22S675; High affinity sodium-glucose cotransporter; Na(+)/glucose cotransporter 1; Na+/glucose cotransporter 1; NAGT; SGLT1; Sodium/glucose cotransporter 1; solute carrier family 5 (sodium/glucose cotransporter), member 1; Solute carrier family 5 member 1
Gene Aliases: D22S675; NAGT; SGLT1; SLC5A1
UniProt ID: (Human) P13866
Entrez Gene ID: (Human) 6523