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Invitrogen
SGLT1 Polyclonal Antibody
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FIGURE: 1 / 7
SGLT1 Antibody (PA5-28240) in ICC/IF
Knockdown of Sodium/glucose cotransporter 1 was achieved by transfecting Caco-2 cells with Sodium/glucose cotransporter 1 specific siRNA (Silencer® select Product # S12952, S12953). Immunofluorescence analysis was performed on untransfected Caco-2 cells (panel a,d), transfected with non-specific scrambled siRNA (panels b,e) and transfected with Sodium/glucose cotransporter 1 specific siRNA (panel c,f). Cells were fixed, permeabilized, and labelled with SGLT1 Polyclonal Antibody (Product # PA5-28240, 1:100 dilution) followed by Donkey anti-... View More
Product Details
PA5-28240
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human SGLT1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Amount
26 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (91%), Rat (91%), Zebrafish (80%), Dog (90%), Cat (89%), Pig (88%), Rabbit (90%), Chicken (82%), Sheep (90%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally-related substances across cellular membranes. Two families of glucose transporter have been identified: the facilitated-diffusion glucose transporter family. The SLC5A1 gene encodes a protein that is involved in the active transport of glucose and galactose into eukaryotic and some prokaryotic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: High affinity sodium-glucose cotransporter; HSGLT1; MGC93553; Na; Na(+)/glucose cotransporter 1; Na+/glucose cotransporter; Na+/glucose cotransporter 1; SLC5A1; sodium glucose cotransporter 1; sodium-glucose cotransporter 1; Sodium/glucose cotransporter 1; solute carrier family 5 (sodium/glucose cotransporter), member 1; Solute carrier family 5 member 1; solute carrier family 5, member 1; solute carrier family 5, member alpha 1; Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter); unnamed protein product
Gene Aliases: D22S675; NAGT; SGLT-1; SGLT1; SLC5A1
UniProt ID: (Human) P13866, (Mouse) Q8C3K6, (Rat) P53790
Entrez Gene ID: (Human) 6523, (Mouse) 20537, (Rat) 25552
galactose transmembrane transporter activity
myo-inositol:sodium symporter activity
water transmembrane transporter activity
glucose:sodium symporter activity
protein binding
pentose transmembrane transporter activity
fucose transmembrane transporter activity
alpha-glucoside transmembrane transporter activity
symporter activity
solute:sodium symporter activity
galactose:sodium symporter activity
transmembrane transporter activity
D-glucose transmembrane transporter activity
transporter activity
glucose transmembrane transporter activity
secondary carrier transporter
alpha-glucoside transport
intestinal D-glucose absorption
ion transport
sodium ion transport
pentose transmembrane transport
fucose transmembrane transport
galactose transport
myo-inositol transport
transepithelial water transport
renal glucose absorption
transmembrane transport
glucose import across plasma membrane
sodium ion import across plasma membrane
intestinal hexose absorption
transport across blood-brain barrier
chloride transmembrane transport
glucose transmembrane transport
metanephros development
transport
carbohydrate transport
glucose transport
hexose transmembrane transport
sodium ion transmembrane transport
intestinal absorption
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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