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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||An 18 amino acid synthetic peptide near the amino terminus of human SGSM3|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||20 ug/ml|
|Immunofluorescence (IF)||20 ug/mL|
|Western Blot (WB)||1 ug/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is 293 cell lysate.
PA5-34451 can be used with blocking peptide PEP-1493.
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. Little is known of the exact function of SGSM3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
MAP; merlin binding protein; merlin-associated protein; rab-GTPase-activating protein-like protein; RABGAP5; RUN and SH3 containing 3; RUN and TBC1 domain containing 3; RUN and TBC1 domain-containing protein 3; RUSC3; RUTBC3; SGSM3; small G protein signaling modulator 3 protein
MAP; RabGAP-5; RABGAP5; RABGAPLP; RUSC3; RUTBC3; SGSM3