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Proteintech
SH3BP5 Polyclonal Antibody
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Product Details
11127-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SH3BP5 Fusion Protein Ag1592 (50-455 aa encoded by BC010123)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EKLNQSTDD INRRETELED ARQKFRSVLV EATVKLDELV KKIGKAVEDS KPYWEARRVA RQAQLEAQKA TQDFQRATEV LRAAKETISL AEQRLLEDDK RQFDSAWQEM LNHATQRVME AEQTKTRSEL VHKETAARYN AAMGRMRQLE KKLKRAINKS KPYFELKAKY YVQLEQLKKT VDDLQAKLTL AKGEYKMALK NLEMISDEIH ERRRSSAMGP RGCGVGAEGS STSVEDLPGS KPEPDAISVA SEAFEDDSCS NFVSEDDSET QSVSSFSSGP TSPSEMPDQF PAVVRPGSLD LPSPVSLSEF GMMFPVLGPR SECSGASSPE CEVERGDRAE GAENKTSDKA NNNRGLSSSS GSGGSSKSQS STSPEGQALE NRMKQLSLQC SKGRDGIIAD IKMVQIG (50-455 aa encoded by BC010123)
Target Information
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: SH3 binding protein; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3-domain binding protein 5 (BTK-associated); SH3BP-5; Vascular endothelial cell-specific protein 18
Gene Aliases: AI606498; SAB; SH3BP-5; SH3BP5; Vesp18
UniProt ID: (Human) O60239, (Rat) Q91Y80, (Mouse) Q9Z131
Entrez Gene ID: (Human) 9467, (Rat) 117186, (Mouse) 24056
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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