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SH3GL2 Antibody (PA5-28466) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SH3GL2 was performed in DIV9 rat E18 primary cortical neurons cells fixed in 4% paraformaldehyde at RT for 15 min. Green: SH3GL2 Polyclonal Antibody (Product # PA5-28466) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-28466
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 177 of Human SH3GL2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545942
Product Specific Information
Recommended positive controls: mouse brain, rat brain.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (87%), Rabbit (87%), Chicken (93%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bA335L15.1; bA335L15.1 (SH3-domain GRB2-like 2); EEN-B1; endophilin; endophilin A1; Endophilin A1 BAR domain; endophilin I; Endophilin-1; Endophilin-A1; FLJ20276; FLJ25015; SH3 domain containing GRB2 like 2; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3-domain GRB2-like 2; SH3p4
Gene Aliases: 9530001L19Rik; AI120490; AW555077; B930049H17Rik; CNSA2; EEN-B1; Een1; SH3D2A; SH3GL2; SH3P4; SH3PA
UniProt ID: (Human) Q99962, (Mouse) Q62420, (Rat) O35179
Entrez Gene ID: (Human) 6456, (Mouse) 20404, (Rat) 116743
regulation of receptor internalization
endocytosis
synaptic vesicle endocytosis
microtubule-based movement
signal transduction
central nervous system development
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of epidermal growth factor receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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