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Proteintech
SH3PXD2A Polyclonal Antibody
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Product Details
18976-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to SH3PXD2A.
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adapter protein TKS5; adaptor protein TKS5; Five SH3 domain-containing protein; five SH3 domains; SH3 and PX domain-containing protein 2A; SH3 multiple domains 1; SH3 multiple domains protein 1; Tyrosine kinase substrate with five SH3 domains
Gene Aliases: 2310014D11Rik; AA589508; AI256723; AI413738; C230050L11; EG329070; FISH; Gm5098; KIAA0418; SH3MD1; SH3PXD2A; TKS5; TSK5
UniProt ID: (Human) Q5TCZ1, (Mouse) O89032
Entrez Gene ID: (Human) 9644, (Rat) 309460, (Mouse) 14218
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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