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Rockland
SH3RF2 Polyclonal Antibody
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FIGURE: 1 / 3
SH3RF2 Antibody (600-401-EH8) in ICC/IF
Immunofluorescence Microscopy of SH3RF2 antibody. Tissue: human brain tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: SH3RF2 antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: SH3RF2 is nuclear. Staining: SH3RF2 as red fluorescent signal.
Product Details
600-401-EH8
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-SH3RF2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human SH3RF2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The SH3RF2 gene encodes a protein that has been shown to possess protein phosphatase 1 binding activity and ubiquitin protein ligase activity. This protein is involved in several cellular processes, including the positive regulation of the JNK cascade, protein autoubiquitination, and regulation of cellular protein metabolic processes. The protein is located in the nucleoplasm and mutations in the SH3RF2 gene have been associated with Ureter Transitional Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase SH3RF2; Heart protein phosphatase 1-binding protein; HEPP1; phosphatase 1 binding protein; POSH-eliminating RING protein; Protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39; putative E3 ubiquitin-protein ligase SH3RF2; RING finger protein 158; RING-type E3 ubiquitin transferase SH3RF2; SH3 domain-containing RING finger protein 2
Gene Aliases: 2310046K19; 9130023G24Rik; AI452083; HEPP1; Posh2; POSH3; POSHER; PPP1R39; RNF158; SH3RF2
UniProt ID: (Human) Q8TEC5, (Rat) Q498M5, (Mouse) Q8C1E3
Entrez Gene ID: (Human) 153769, (Rat) 307472, (Mouse) 269016
protein phosphatase inhibitor activity
protein binding
protein phosphatase 1 binding
zinc ion binding
ligase activity
phosphatase binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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