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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SHC3 Antibodies

          Invitrogen

          SHC3 Polyclonal Antibody

          View all (11) SHC3 antibodies

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          Cite SHC3 Polyclonal Antibody

          • Antibody Testing Data (2)
          SHC3 Antibody in Immunocytochemistry (ICC/IF)
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          SHC3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          SHC3 Antibody (PA5-65099) in ICC/IF

          Immunofluorescent staining of SHC3 in human cell line AF22 shows localization to nucleoplasm. Samples were probed using a SHC3 Polyclonal Antibody (Product # PA5-65099). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SHC3 Antibody in Immunocytochemistry (ICC/IF)
          SHC3 Antibody in Western Blot (WB)
          SHC3 Polyclonal Antibody

          Product Details

          PA5-65099

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human SHC3. Recombinant protein control fragment (Product #RP-96520).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2664262

          Product Specific Information

          Immunogen sequence: HPYYNSIPSKM PPPGGFLDTR LKPRPHAPDT AQFAGKEQTY YQGRHLGDTF GEDWQQTPLR QGSSDIYSTP EGKLHVAPTG EAPTYVNTQQ IPP

          Highest antigen sequence identity to the following orthologs - mouse 81%, rat 81%.

          Target Information

          Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: N-Shc; Neuronal Shc; Protein Rai; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHC-transforming protein 3; SHC-transforming protein C; Shc3 p51; src homology 2 domain-containing transforming protein C3; Src homology 2 domain-containing-transforming protein C3

          View more View less

          Gene Aliases: N-Shc; NSHC; RAI; SHC3; SHCC

          View more View less

          UniProt ID: (Human) Q92529

          View more View less

          Entrez Gene ID: (Human) 53358

          View more View less

          Function(s)
          signal transducer activity Ras guanyl-nucleotide exchange factor activity protein binding receptor tyrosine kinase binding scaffold/adaptor protein
          Process(es)
          MAPK cascade transmembrane receptor protein tyrosine kinase signaling pathway epidermal growth factor receptor signaling pathway Ras protein signal transduction central nervous system development learning or memory synaptic transmission, glutamatergic positive regulation of GTPase activity
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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