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Proteintech
SHKBP1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
12703-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SHKBP1 Fusion Protein Ag3386 (358-707 aa encoded by BC022855)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.15 mg/mL
Amount
22.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKDNDLLVS ELYRDPAEDG VTALSVYLTP KTSDSGNWIE IAYGTSSGGV RVIVQHPETV GSGPQLFQTF TVHRSPVTKI MLSEKHLISV CADNNHVRTW SVTRFRGMIS TQPGSTPLAS FKILALESAD GHGGCSAGND IGPYGERDDQ LVFIQKVVPS ASQLFVRLSS TGQRVCSVRS VDGSPTTAFT VLECEGSRRL GSRPRRYLLT GQANGSLAMW DLTTAMDGLG QAPAGGLTEQ ELMEQLEHCE LAPPAPSAPS WGCLPSPSPR ISLTSLHSAS SNTSLSGHRG SPSPPQAEAR RRGGGSFVER CQELVRSGPD LRRPPTPAPW PSSGLGTPLT PPKMKLNETS F (358-707 aa encoded by BC022855)
Target Information
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: multifunctional adaptor protein; SETA binding protein 1; SETA-binding protein 1; unnamed protein product
Gene Aliases: B930062H15Rik; PP203; RGD1309281; Sb1
UniProt ID: (Human) Q8TBC3, (Mouse) Q6P7W2, (Rat) P0C5J9
Entrez Gene ID: (Human) 92799, (Mouse) 192192, (Rat) 292735
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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