Immunogen sequence: PPLLIQDEDS TRIERVMDNN TTVKMVPIKI VHSESQPEKE SRQSLACPAE PPALPHGLEK DQIKTLSTSE QFYS
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 89%.
The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.
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Protein Aliases: Apical-like protein; APX homolog of Xenopus; Protein APXL; Protein Shroom2
Gene Aliases: APXL; HSAPXL; SHROOM2
UniProt ID: (Human) Q13796
Entrez Gene ID: (Human) 357