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Invitrogen
SI Polyclonal Antibody
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FIGURE: 1 / 4
SI Antibody (PA5-95609) in IHC (P)
Immunohistochemistry (Paraffin) analysis of SI in paraffin-embedded section of mouse small intestine tissue using SI Polyclonal Antibody (Product # PA5-95609). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution overnight at ... View More
Product Details
PA5-95609
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human SI (FQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDID).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat small intestine tissue. IHC: mouse small intestine tissue, rat small intestine tissue. Flow: CACO-2 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-glucosidase; Alpha-methylglucosidase; Oligo-1,6-glucosidase; oligosaccharide alpha-1,6-glucosidase; sucrase isomaltase, structural; sucrase-isomaltase; Sucrase-isomaltase, intestinal
Gene Aliases: 2010204N08Rik; SI; Si-s; SUCIMAL
UniProt ID: (Human) Q1JQ80
Entrez Gene ID: (Human) 6476, (Rat) 497756, (Mouse) 69983
catalytic activity
hydrolase activity, hydrolyzing O-glycosyl compounds
alpha-1,4-glucosidase activity
oligo-1,6-glucosidase activity
sucrose alpha-glucosidase activity
protein binding
hydrolase activity
hydrolase activity, acting on glycosyl bonds
carbohydrate binding
alpha-glucosidase activity
beta-fructofuranosidase activity
glucosidase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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