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Invitrogen
SIDT1 Polyclonal Antibody
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Product Details
PA5-79998
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human SIDT1 (36-52aa RRDPFDAARGADFDHVY).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA Cell, COLO320 Cell, SW620 Cell, HT1080 Cell.
Target Information
The SIDT1 gene encodes the SID1 transmembrane family member 1 protein, which is involved in RNA transport and may play a role in RNA silencing pathways. SIDT1 has been studied for its role in facilitating the uptake and cellular exchange of double-stranded RNA (dsRNA), a process that is crucial for gene regulation and immune responses. The protein's activity is thought to be involved in RNA interference (RNAi), a mechanism for silencing genes that are complementary to an introduced dsRNA. SIDT1's function is important for maintaining RNA homeostasis and regulating gene expression, impacting various cellular processes and potential therapeutic applications, such as antiviral strategies and cancer treatment. Understanding the role of SIDT1 in RNA transport and the RNAi pathway provides insights into how cells manage genetic and environmental information, which could be pivotal for developing RNA-based therapeutic interventions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SID1 transmembrane family member 1; unnamed protein product
Gene Aliases: SID-1; SID1; SIDT1
UniProt ID: (Human) Q9NXL6
Entrez Gene ID: (Human) 54847
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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