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Invitrogen
SIM1 Polyclonal Antibody
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FIGURE: 1 / 1
SIM1 Antibody (PA5-121467) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of SIM1 in Hela cells using SIM1 Polyclonal Antibody (Product # PA5-121467) at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product Details
PA5-121467
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Single-minded homolog 1 protein (347-434aa)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody tested in Indirect ELISA
Target Information
SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis, it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHe14; Class E basic helix-loop-helix protein 14; Single-minded homolog 1
Gene Aliases: BHLHE14; SIM1
UniProt ID: (Human) P81133
Entrez Gene ID: (Human) 6492
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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