Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Histone deacetylase complex subunit Sin3b; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b; transcriptional regulator, SIN3 yeast homolog B
Gene Aliases: 2810430C10Rik; KIAA0700; SIN3B
UniProt ID: (Human) O75182, (Mouse) Q62141
Entrez Gene ID: (Human) 23309, (Mouse) 20467
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